Inosine-5'-monophosphate dehydrogenase 2 Polyclonal Antibody

Catalog Number:

42226

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P12268

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Inosine-5'-monophosphate dehydrogenase 2 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Inosine-5'-monophosphate dehydrogenase 2 polyclonal antibody.

Applications:

WB

Background:

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

References:

[1]Cloning and sequence analysis of the human and Chinese hamster inosine-5'-monophosphate dehydrogenase cDNAs.Collart F.R., Huberman E.J. Biol. Chem. 263:15769-15772(1988) [2]Two distinct cDNAs for human IMP dehydrogenase.Natsumeda Y., Ohno S., Kawasak

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF