Integrin-linked kinase-associated serine/threonine phosphatase 2C Polyclonal Antibody

Catalog Number:

42223

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H0C8

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Integrin-linked kinase-associated serine/threonine phosphatase 2C protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Integrin-linked kinase-associated serine/threonine phosphatase 2C polyclonal antibody.

Applications:

WB

Background:

Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation

References:

[1]"Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1."Leung-Hagesteijn C., Mahendra A., Naruszewicz I., Hannigan G.E. EMBO J. 20:2160-2170(2001) [2]"Towards

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF