Peroxiredoxin-1 Polyclonal Antibody

Catalog Number:

42222

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q06830

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Peroxiredoxin-1 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Peroxiredoxin-1 polyclonal antibody.

Applications:

WB IHC

Background:

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation

References:

[1]"A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins."Prosperi M.T., Ferbus D., Karczinski I., Goubin G.J. Biol. Chem. 268:11050-11056(1993) [2]"Cloning an

appl_detail:

Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200

Datasheet PDF