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Catalog Number: |
42209 |
| other_names: | hnRNP M, HNRNPM, HNRPM, NAGR1 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: P52272 |
Form of Antibody: |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage/Stability: |
|
Immunogen: |
Recombinant human Heterogeneous nuclear ribonucleoprotein M protein (491-730aa) |
Purification: |
Antigen Affinity Purified |
Specificity/Sensitivity: |
The antibody detects endogenous level of total HNRNPM polyclonal antibody. |
Applications: |
IHC |
Background: |
Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. |
References: |
1"Solution structure of the RNA binding domains of heterogeneous nuclear ribonucleoprotein M." RIKEN structural genomics initiative (RSGI)Submitted (OCT-2006). [2]"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and i |
appl_detail: |
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