3-hydroxy-3 methylglutaryl-coenzyme A reductase Polyclonal Antibody

Catalog Number:

42206

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P04035

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total 3-hydroxy-3 methylglutaryl-coenzyme A reductase polyclonal antibody.

Applications:

WB

Background:

Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

References:

[1] "Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation." Luskey K.L., Stevens B.J. Biol. Chem. 260:10271-10277(1985) [2] "Human HMG-CoA reductase gene."Nakajima

appl_detail:

Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200

Datasheet PDF