GBP1 Polyclonal Antibody

Catalog Number:

42176

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P32455

Form of Antibody:

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage/Stability:

Immunogen:

Recombinant human Interferon-induced guanylate-binding protein 1 protein (383-592aa)

Purification:

Antigen Affinity Purified

Specificity/Sensitivity:

The antibody detects endogenous level of total GBP1 polyclonal antibody.

Applications:

WB IHC

Background:

Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

References:

[1]"How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP." Ghosh A., Praefcke G.J., Renault L., Wittinghofer A., Herrmann C.Nature 440:101-104(2006). [2]"Triphosphate structure of guanylate-binding protein 1 and imp

appl_detail:

Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:20 - 1:200

Datasheet PDF