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Arylsulfatase B Polyclonal Antibody

Catalog Number:

42072
other_names: N-acetylgalactosamine-4-sulfatase ARSB

Amount:

100μg
calculated_mw: 38kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P15848

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Arylsulfatase B protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Arylsulfatase B polyclonal antibody.

Applications:

WB

Background:

Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity).

References:

[1]Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B.Peters C., Schmidt B., Rommerskirch W., Rupp K., Zuehlsdorf M., Vingron M., Meyer H.E., Pohlmann R., von Figura K.J. Biol. Chem. 265:3374-3381(1990) [2]

appl_detail:

Western blotting: 1:500 - 1:1000

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