MANF Polyclonal Antibody

Catalog Number:

42071

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P55145

Form of Antibody:

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage/Stability:

Immunogen:

Recombinant human Mesencephalic astrocyte-derived neurotrophic factor protein(25-182aa)

Purification:

Antigen Affinity Purified

Specificity/Sensitivity:

The antibody detects endogenous level of total MANF polyclonal antibody.

Applications:

IHC

Background:

Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.

References:

[1]Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer."Shridhar V., Rivard S., Wang X., Shridhar R., Paisley C., Mullins C., Beirnat L., Dugan M., Sarkar F., Miller O.J., Vaitkevicius V.K., Smith D.I.Oncogene 14:2213-2216(1997). [2]Mut

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF