Casein kinase I isoform epsilon Polyclonal Antibody

Catalog Number:

42244

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P49674

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Casein kinase I isoform epsilon protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Casein kinase I isoform epsilon polyclonal antibody.

Applications:

WB

Background:

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.

References:

[1]"Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family."Fish K.J., Cegielska A., Getman M.E., Landes G.M., Virshup D.M.J. Biol. Chem. 270:14875-14883(1995) [2]"Casein kinase I epsilon from HeLa ce

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF