Phosphoglycerate kinase 1 Polyclonal Antibody

Catalog Number:

42053

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P00558

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Phosphoglycerate kinase 1 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Phosphoglycerate kinase 1 polyclonal antibody.

Applications:

WB

Background:

Also known as ATP:3-phosphoglycerate 1-phosphotransferase, this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. In addition to its role as a glycolytic enzyme, PGK-1 appears to acts as a polymerase alpha cofactor protein. Defects in PGK1 are generally associated with chronic hemolytic anemia.

References:

[1] "Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase."Michelson A.M., Markham A.F., Orkin S.H.Proc. Natl. Acad. Sci. U.S.A. 80:472-476(1983) [2] "Structure of the human phosphoglycerate kina

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF