MX1 antibody

Catalog Number:

38296

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P20591
NCBI Gene ID: 4599

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human MX1.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total MX1 antibody.

Applications:

WB

Background:

Mx1 (also known as MxA) is a GTPase that belongs to the Mx family of proteins, which are ubiquitous in eukaryotes and involved in the immune response to viral infections. The human Mx1 is localized in the cytoplasm interfering with the translation of viral proteins, whereas the mouse Mx1 accumulates in the nucleus and inhibits the primary transcription of viral RNA. Mx1 expression is induced by treatment with α/β interferon (INF). This antibody can recognize the endogenous Mx1 protein in several tissues like lung and spleen.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF