PAPPA Antibody

Catalog Number:

37794

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13219
NCBI Gene ID: 5069
Gene Accssion: NP_002572

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human pregnancy-associated plasma protein A, pappalysin 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PAPPA protein.

Applications:

IHC

Background:

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF