NEFH Antibody

Catalog Number:

37759

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P12036
NCBI Gene ID: 4744
Gene Accssion: NP_066554

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human neurofilament, heavy polypeptide

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NEFH protein.

Applications:

IHC

Background:

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF