NLRP6 Antibody

Catalog Number:

37752

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P59044
NCBI Gene ID: 171389
Gene Accssion: NP_612202

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human NLR family, pyrin domain containing 6

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NLRP6 protein.

Applications:

IHC

Background:

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF