NLRP12 Antibody

Catalog Number:

37750

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P59046
NCBI Gene ID: 91662
Gene Accssion: NP_653288

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human NLR family, pyrin domain containing 12

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NLRP12 protein.

Applications:

IHC

Background:

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF