TRPV1 Antibody

Catalog Number:

37726

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8NER1
NCBI Gene ID: 7442
Gene Accssion: NP_542435

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human transient receptor potential cation channel, subfamily V, member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRPV1 protein.

Applications:

IHC

Background:

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF