MDFIC Antibody

Catalog Number:

37721

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9P1T7
NCBI Gene ID: 29969
Gene Accssion: NP_001159817

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human MyoD family inhibitor domain containing

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MDFIC protein.

Applications:

IHC

Background:

This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF