KCNMB3 Antibody

Catalog Number:

37679

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NPA1
NCBI Gene ID: 27094
Gene Accssion: NP_055222

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human potassium large conductance calcium-activated channel, subfamily M beta member 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KCNMB3 protein.

Applications:

IHC

Background:

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF