KDM4C Antibody

Catalog Number:

37672

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H3R0
NCBI Gene ID: 23081
Gene Accssion: NP_055876

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human lysine (K)-specific demethylase 4C

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KDM4C protein.

Applications:

WB

Background:

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF