ITPR3 Antibody

Catalog Number:

37667

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14573
NCBI Gene ID: 3710
Gene Accssion: NP_002215

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human inositol 1,4,5-trisphosphate receptor, type 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ITPR3 protein.

Applications:

IHC

Background:

This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF