ICAM5 Antibody

Catalog Number:

37639

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UMF0
NCBI Gene ID: 7087
Gene Accssion: NP_003250

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human intercellular adhesion molecule 5, telencephalin

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ICAM5 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Datasheet PDF