HRG Antibody

Catalog Number:

37628

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P04196
NCBI Gene ID: 3273
Gene Accssion: NP_000403

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human histidine-rich glycoprotein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HRG protein.

Applications:

IHC

Background:

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF