HOXB8 Antibody

Catalog Number:

37627

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P17481
NCBI Gene ID: 3218
Gene Accssion: NP_076921

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human homeobox B8

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HOXB8 protein.

Applications:

WB

Background:

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF