HMGCS2 Antibody

Catalog Number:

37623

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P54868
NCBI Gene ID: 3158
Gene Accssion: NP_005509

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HMGCS2 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Datasheet PDF