GALC Antibody

Catalog Number:

37586

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P54803
NCBI Gene ID: 2581
Gene Accssion: NP_000144

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human galactosylceramidase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GALC protein.

Applications:

WB

Background:

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF