SPAST Antibody

Catalog Number:

37577

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UBP0
NCBI Gene ID: 6683
Gene Accssion: NP_055761

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human spastin

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SPAST protein.

Applications:

IHC

Background:

This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF