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ENDOG Antibody

Catalog Number:

37547
other_names: Endo G; ENDOG; endonuclease G; Endonuclease G; mitochondrial; FLJ27463; NUCG

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14249
NCBI Gene ID: 2021
Gene Accssion: NP_004426

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human endonuclease G

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ENDOG protein.

Applications:

IHC

Background:

The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

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