KCNB1 Antibody

Catalog Number:

37539

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14721
NCBI Gene ID: 3745
Gene Accssion: NP_004966

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human potassium voltage-gated channel, Shab-related subfamily, member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KCNB1 protein.

Applications:

IHC

Background:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF