DICER1 Antibody

Catalog Number:

37534

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UPY3
NCBI Gene ID: 23405
Gene Accssion: NP_085124

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human dicer 1, ribonuclease type III

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DICER1 protein.

Applications:

IHC

Background:

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF