DSG1 Antibody

Catalog Number:

37531

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q02413
NCBI Gene ID: 1828
Gene Accssion: NP_001933

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human desmoglein 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DSG1 protein.

Applications:

WB

Background:

Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF