DSC1 Antibody

Catalog Number:

37529

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q08554
NCBI Gene ID: 1823
Gene Accssion: NP_077739

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human desmocollin 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DSC1 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF