CSMD1 Antibody

Catalog Number:

37511

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96PZ7
NCBI Gene ID: 64478
Gene Accssion: NP_150094

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CUB and Sushi multiple domains 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CSMD1 protein.

Applications:

IHC

Background:

CSMD1 CUB and Sushi multiple domains 1 is a?protein?that in humans is encoded by the?CSMD1gene. It is a potential tumour?suppressor, the deletion of which may result in head and neck?carcinomas?behaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF