COL7A1 Antibody

Catalog Number:

37510

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q02388
NCBI Gene ID: 1294
Gene Accssion: NP_000085

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human collagen, type VII, alpha 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total COL7A1 protein.

Applications:

IHC

Background:

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF