TNFRSF8 Antibody

Catalog Number:

37469

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P28908
NCBI Gene ID: 943
Gene Accssion: NP_001234

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human tumor necrosis factor receptor superfamily, member 8

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TNFRSF8 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF