CARD17 Antibody

Catalog Number:

37461

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5XLA6
NCBI Gene ID: 440068
Gene Accssion: NP_001007233

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human caspase recruitment domain family, member 17

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CARD17 protein.

Applications:

IHC

Background:

Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF