CAPZA1 Antibody

Catalog Number:

37459

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P52907
NCBI Gene ID: 829
Gene Accssion: NP_006126

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human capping protein (actin filament) muscle Z-line, alpha 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CAPZA1 protein.

Applications:

IHC

Background:

CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF