BOD1 Antibody

Catalog Number:

37445

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96IK1
NCBI Gene ID: 91272
Gene Accssion: NP_001153123

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human biorientation of chromosomes in cell division 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BOD1 protein.

Applications:

IHC

Background:

Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.?Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF