SLC4A1 Antibody

Catalog Number:

37439

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P02730
NCBI Gene ID: 6521
Gene Accssion: NP_000333

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human solute carrier family 4 (anion exchanger), member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC4A1 protein.

Applications:

IHC

Background:

The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF