BAI1 Antibody

Catalog Number:

37437

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O14514
NCBI Gene ID: 575
Gene Accssion: NP_001693

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human brain-specific angiogenesis inhibitor 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BAI1 protein.

Applications:

IHC

Background:

Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF