ERAP1 Antibody

Catalog Number:

37429

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NZ08
NCBI Gene ID: 51752
Gene Accssion: NP_001035548

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human endoplasmic reticulum aminopeptidase 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ERAP1 protein.

Applications:

WB

Background:

The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF