NLRP7 Antibody

Catalog Number:

37421

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8WX94
NCBI Gene ID: 199713
Gene Accssion: NP_001120727

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human NLR family, pyrin domain containing 7

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NLRP7 protein.

Applications:

IHC

Background:

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF