DEFA5 Antibody

Catalog Number:

37411

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q01523
NCBI Gene ID: 1670
Gene Accssion: NP_066290

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human defensin, alpha 5, Paneth cell-specific

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DEFA5 protein.

Applications:

IHC

Background:

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF