DEFA1/3 Antibody

Catalog Number:

37410

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P59665/P59666
NCBI Gene ID: 1667/1668
Gene Accssion: NP_004075/NP_005208

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human defensin, alpha 1/3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DEFA1/3 protein.

Applications:

IHC

Background:

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Defensin, alpha Several alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF