SLC6A4 Antibody

Catalog Number:

37406

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P31645
NCBI Gene ID: 6532
Gene Accssion: NP_001036

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 6 (neurotransmitter transporter), member 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC6A4 protein.

Applications:

IHC

Background:

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF