SEPT4 Antibody

Catalog Number:

37398

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O43236
NCBI Gene ID: 5414
Gene Accssion: NP_004565

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human septin 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SEPT4 Antibody.

Applications:

IHC

Background:

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF