SPR Antibody

Catalog Number:

37391

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P35270
NCBI Gene ID: 6697
Gene Accssion: NP_003115

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SPR protein.

Applications:

WB IHC

Background:

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

Datasheet PDF