PFKFB2 Antibody

Catalog Number:

37382

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60825
NCBI Gene ID: 5208
Gene Accssion: NP_001018063

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PFKFB2 protein.

Applications:

WB

Background:

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.?

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF