GIPR Antibody

Catalog Number:

37370

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P48546
NCBI Gene ID: 2696
Gene Accssion: NP_000155

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human gastric inhibitory polypeptide receptor

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GIPR protein.

Applications:

WB

Background:

This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF