AGL Antibody

Catalog Number:

37366

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P35573
NCBI Gene ID: 178
Gene Accssion: NP_000019

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AGL protein.

Applications:

IHC

Background:

This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF