INTS1 Antibody

Catalog Number:

37357

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8N201
NCBI Gene ID: 26173
Gene Accssion: NP_001073922

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human integrator complex subunit 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total INTS1 protein.

Applications:

IHC

Background:

INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1 and U2. RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF